Polycythaemia

Definition/Description

Female: Haematocrit >0.48 / Male: Haematocrit >0.52

Red Flag Symptoms

Urgent referral if any of the following:

  • Female: Hct>0.56 / Male: Hct >0.60 in the absence of congenital cyanotic heart disease
  • Arterial or venous thromboembolism within the last 3 months
  • Unexplained visual loss (also refer to eye clinic)
  • Abnormal bleeding (if serious please discuss with the on call haematology team via switch)

Guidelines on Management

If none of the above, then repeat in 2 months and consider secondary causes:

  • Diuretics, testosterone replacement, anabolic steroids, empagliflozin, dapagliflozin
  • Chronic hypoxia
  • Smoking or alcohol excess
  • Dehydration at the time of the test

If secondary causes present, address where possible (eg stop causative medications, lifestyle advice) and repeat in 3 months.

If no obvious secondary cause and persistently Hct >0.48 (female) / Hct>0.52 (male), send JAK2 and refer routinely to haematology.

Note: patients with erythrocytosis should not be given iron replacement.

Referral Criteria/Information

None provided

Associated Policies

There are no associated policies.

Specialties

Places covered by

  • vale-of-york

Hospital Trusts

  • york-and-scarborough-teaching-hospitals
Author: York and Scarborough Teaching Hospitals NHSFT Haematology Consultant Team
Date created: 18/06/2025, 15:14
Last modified: 26/06/2025, 15:19
Date of review: 2027/3/31