Haematology
Policies
Pathways
Additional information
As detailed in the directory of services, the haematology team do not investigate or manage raised ferritin, iron overload or haemochromatosis.
If formal iron studies (serum ferritin with concomitant CRP, serum iron, transferrin and transferrin saturation) were to suggest iron overload then 2 x EDTA tubes can be sent to the lab with a request for genetic testing to confirm or exclude haemochromatosis. This takes 8-12 weeks to report. If the iron studies do not suggest overload and you have clinical concern then other causative factors such as alcohol consumption, obesity, diabetes, liver disease, renal disease, malignancy, infection or inflammation need to be considered.
Patients with confirmed haemochromatosis and concomitant iron overload / hepatic impairment should be discussed with hepatology.
There is a helpful table covering result interpretation under “Interpreting results” at https://labtestsonline.org/tests/transferrin-and-iron-binding-capacity-tibc-uibc.
The BCSH guideline on the investigation and management of raised ferritin is also useful: https://onlinelibrary.wiley.com/doi/epdf/10.1111/bjh.15166