Lymphadenopathy
Definition/Description
Swelling of lymph nodes
Red Flag Symptoms
None provided
Guidelines on Management
Causes
- Acute and chronic bacterial infections
- Syphilis
- Auto-immune conditions
- Malignancy (haematological / matastatic)
- Viral infections (including HIV, EBV, CMV)
Referral Criteria/Information
Refer to Haematology as urgent (suspected cancer pathway) if has lympadenopathy associated with:
- B symptoms
- Weight loss >10% over 6 months
- Drenching sweats
- Unexplained fever >38°C
- Liver and spleen enlargement
- Rapidly increasing in size
- Generalised lymphadenopathy
- Cytopenias
Appropriate referral to surgical team or ENT for biopsy / radiological biopsy (US or CT guidance) if:
- Localised unexplained adenopathy
OR - Concerns of metastatic node
Associated Policies
There are no associated policies.
Specialties
Places covered by
- North Yorkshire
Hospital Trusts
Harrogate and District
Date created: 17/03/2026, 16:11
Last modified: 17/03/2026, 16:12
Date due for review: 17/03/2028