Primary Endocrine Treatment For Breast Cancer

Definition/Description

The majority of patients diagnosed with breast cancer will have surgery and adjuvant treatment. For those who have oestrogen or progesterone receptor positive tumours endocrine treatment will form part of the adjuvant therapy.

However there is a small cohort of patients who have oestrogen or progesterone receptor positive tumours in whom surgery is not appropriate:

  • Significant comorbidity (may not survive a general anaesthetic)
  • Other life limiting conditions
  • Patient wishes
  • Family wishes if have power of attorney for all medical matters

These patients may be offered palliative treatment with the aromatase inhibitor letrozole.

Red Flag Symptoms

No Red Flags Listed

Guidelines on Management

Patients with difficulty walking /wheelchair bound and resident in a care home etc require a considerable upheaval for both  patients and carers for a 5 minute hospital assessment. These patients can be followed up by the GP.

If a patient has stable or regressing disease after 1 year of letrozole the GP will follow patients up at their residence/home as below:`

  • Patient discharged from secondary care with a discharge summary for GP to follow the primary endocrine follow up.
  • GP to assess the patient breast mass clinically yearly with/without callipers in two largest dimensions.
  • If there is no progression of disease or regression -continue yearly follow up.
  • If progression refer back to breast clinic in secondary care.
  • If symptoms of systemic relapse refer to breast clinic

Referral Criteria/Information

No Referral Criteria/Information Listed

Associated Policies

There are no associated policies.

Specialties

There are no associated specialties.

Places covered by

  • East Riding
  • Hull

Hospital Trusts

  • Hull University Teaching Hospitals
Author:
Date created: 02/07/2025, 14:11
Last modified: 02/07/2025, 14:17
Date of review: 01/06/2025