Dysmenorrhoea

Definition/Description

Primary Dysmenorrhoea:

  • Period pains not associated with underlying pathology
  • Usually D1-3 of menses, present from menarche
     

Secondary Dysmenorrhoea:

  • Painful periods suggestive of underlying pathology
  • Eg. Endometriosis, adenomyosis, PID presents in 20-30yrs olds
  • Pain often persists for 1-7d after menstruation ends

Red Flag Symptoms

  • Consider Pelvic Inflammatory Disease (acute or chronic) especially in the under 25s with new onset
  • Ovarian cancer can cause bloating and lower abdominal pain, see NICE Guidance for Ovarian Cancer.

Guidelines on Management

Primary dysmenorrhoea

  • Offer NSAID such as ibuprofen, naproxen, or mefenamic acid unless contraindicated. Mefenamic acid is licensed for the treatment of dysmenorrhoea, however be aware that there are concerns that it is more likely to cause seizures in overdose than other NSAIDs.
  • Offer paracetamol if NSAIDs are contraindicated or not tolerated, or in addition to an NSAID if the response is insufficient.
  • If the woman does not wish to conceive, consider prescribing a 3–6 month trial of hormonal contraception:
  • Monophasic combined oral contraceptive (COC) preparations containing 30–35 micrograms of ethinylestradiol and norethisterone, norgestimate, or levonorgestrel are usually first choice.
  • Oral (desogestrel 75 micrograms), parenteral (Depo-Provera® or Sayana Press®, and Nexplanon® and intrauterine progestogen-only (Mirena®) contraceptives may also be considered, after a full discussion of the advantages and disadvantages.
  • Combination of an NSAID (or paracetamol) and hormonal contraception is also an option if the response to individual treatments is insufficient.
  • In addition to drug treatments consider the following non-drug measures to reduce pain:
    • Local application of heat (for example, a hot water bottle or heat patch); Transcutaneous electrical nerve stimulation (TENS) — set to a high frequency
       

Secondary dysmenorrhoea

  • Secondary causes for dysmenorrhoea must be excluded before considering a diagnosis of primary dysmenorrhoea.

Referral Criteria/Information

Indications for referral

  • Pain not controlled by management above or pelvic pathology suspected
     

Information to include in referral letter

  • History of problem and effect on activities of daily living (commonest cause of school absence in girls) and impact on work.
  • History of any IMB or PCB
  • Examination (will depend on age/ whether sexually active)
  • Swabs – HVS and ECS
  • Bimanual - check for cervical excitation/ uterine mobility and tenderness/ retrovaginal nodules (endometriosis)
  • Smear - if over 25 and due.
  • Any image results if available
     

Investigations prior to referral

  • Consider a pelvic USS if pathology is suspected

Additional Resources & Reference

Patient information leaflets/ PDAs

http://www.patient.co.uk/health/period-pain-dysmenorrhoea

Endometriosis
https://www.eshre.eu/Guidelines-and-Legal/Guidelines/Endometriosis-guideline.aspx
 

References

NICE CKS Guidelines – Dysmenorrhoea – May 2014 https://www.nice.org.uk/Guidance/CG122 

Associated Policies

There are no associated policies.

Specialties

Places covered by

  • Vale of York

Hospital Trusts

  • York and Scarborough Teaching Hospitals
Author: Responsible GP: Dr Joan Meakins / Responsible Consultant: Miss F Sanaullah / Responsible Pharmacist: Laura Angus
Date created: 13/08/2025, 08:48
Last modified: 13/08/2025, 08:48
Date of review: 9/30/24